The bacteria E. coli, prefers to adhere to D-Mannose as it passes through the urinary tract rather than the cell walls. D-Mannose supports a healthy urinary tract by creating an environment where bacteria find it difficult to stick to the cellular surface. It can be used frequently at a dose of every two hours and symptoms will usually abate within 48 hours. If this two day mark is reached with no improvement we strongly bid you seek your doctor's advice with urgency.

We have been asked many times if D-Mannose may be used as a preventative treatment and if so what is the dose. The answer to the first part is “Yes, it can” . The question of dosage depends on the person. Rather than give a standard recommendation for everybody which would work in most cases but could possibly be wasting the product we suggest that our clients experiment to find the minimal dose frequency that works in practice.

At the first sign of an attack we recommend the acute dose: Two 1.25ml teaspoonsful in a large glass of water taken every two hours and as extra water in between doses if you can manage it, during waking hours.

Some people suffer almost constant urinary tract infections. It seems as if they have just cleared one infection and another begins. Often there is some structural problem that prevents urine from being cleared properly and re-infection may be frequent. In planning a strategy of prevention a couple of things needs to be considered. Keeping the urine flow at a higher level is a good idea so frequent fluid intake is important as is paying attention to personal hygiene. A daily dosage regime of D-Mannose to prevent bacteria colonising is also helpful.

We suggest that initial dosing should start at 2-3 times per day. If no infection recurs over a two week period then drop the dose down by 1 to 1-2 times per day for another two weeks. If still no sign of symptoms drop down to once a day. If any sign of infection occurs go straight back to the attack treatment mentioned above for two days before resuming at the last level that kept you free of attacks. You are seeking the smallest daily dose that will keep you clear of infection. For some this means only one dose every 2 or 3 days while others require at least one dose per day.

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